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Metabolic disorders such as obesity and diabetes are frequently associated with gut dysbiosis, characterized by reduced microbial diversity, loss of beneficial taxa, and increased inflammatory signatures, which contributes to insulin resistance and metabolic impairment (710)
Later, it was discovered that mitochondrial DNA encodes its own small biologically active peptides that are released from the mitochondria and act as hormone-like signaling molecules throughout the body
doi: 10.1089/ars.2010.3496 97 GhatiA.DamP.TasdemirD.KatiA.SellamiH.SezginG
Duca and other researchers are beginning to show that particular types of fibers are more potent at triggering GLP-1 release and at regulating hunger than others
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